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Cytoplasmic Alteration (Figure 44) Synonyms Cytoplasmic alteration, cytoplasmic change, granular change, granular degeneration, hyaline degeneration, glycogen accumulation

These three use cases reflect different biological contexts and different expected time horizons for response

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Conversely, the M2 phenotype supports tissue repair and synaptic remodeling following the pro-inflammatory phase through the secretion of anti-inflammatory cytokines [i.e., IL-10 and transforming growth factor-beta (TGF-)]